Predictive Performance of Pre-Hajj Health Screening for Morbidity, Hospitalization and Mortality
DOI:
https://doi.org/10.59890/ijgsr.v4i10.9Keywords:
Pre-Hajj Health Screening, Hajj Pilgrims, Predictive Performance, Risk Prediction Model, Morbidity, Hospitalization, Mortality, Mass Gathering MedicineAbstract
Background: Hajj is one of the largest annual mass gatherings worldwide, involving millions of pilgrims with diverse health conditions and vulnerabilities. Pre-Hajj health screening is widely implemented to identify high-risk pilgrims; however, its ability to predict morbidity, hospitalization, and mortality remains unclear. Objective: This systematic review aimed to evaluate the predictive performance of pre-Hajj health screening components for adverse clinical outcomes among Hajj pilgrims and identify gaps in current risk prediction approaches. Methods: A systematic literature review was conducted following the PRISMA 2020 guidelines. Studies published from January 2020 to 2026 were identified through Scopus, PubMed/MEDLINE, Web of Science, and additional sources. Eligible studies evaluated pre-Hajj health assessment variables, including demographic characteristics, chronic diseases, cardiovascular risk factors, and functional status, in relation to morbidity, hospitalization, or mortality outcomes. Evidence was synthesized narratively based on predictive factors, analytical approaches, and methodological limitations. Results: The findings demonstrated that advanced age, diabetes mellitus, hypertension, cardiovascular disease, multimorbidity, and functional impairment were consistently associated with adverse Hajj outcomes. However, most studies focused on identifying risk factors rather than developing validated prediction models. Measures of predictive performance, including discrimination, calibration, and external validation, were rarely reported, indicating that current screening systems remain primarily risk identification tools rather than individualized prediction models
References
Aldossari, M. R., Aljoudi, A., & Celentano, D. (2019). Health issues in the Hajj pilgrimage: A literature review. Eastern Mediterranean Health Journal, 25(10), 744–753. https://doi.org/10.26719/2019.25.10.744
Alfelali, M., et al. (2024). Epidemiology of Hajj pilgrimage mortality: Analysis for potential intervention. Journal of Infection and Public Health, 17(Suppl 1), 49–61. https://doi.org/10.1016/j.jiph.2023.05.021
Alqahtani, A. S., Tashani, M., Heywood, A. E., Almohammed, A. B. S., Booy, R., Wiley, K. E., & Rashid, H. (2020). Tracking Australian Hajj pilgrims’ health behavior before, during and after Hajj, and the effective use of preventive measures in reducing Hajj-related illness: A cohort study. Pharmacy, 8(2), 78. https://doi.org/10.3390/pharmacy8020078
Al-Shimemeri, A. (2012). Cardiovascular disease in Hajj pilgrims. Journal of the Saudi Heart Association, 24(2), 123–127. https://doi.org/10.1016/j.jsha.2012.02.004
Ardiana, M., Utami, E. R., Al Farabi, M. J., & Azmi, Y. (2023). The impact of classical cardiovascular risk factors on hospitalization and mortality among Hajj pilgrims. The Scientific World Journal, 2023, 9037159. https://doi.org/10.1155/2023/9037159
Collins, G. S., Moons, K. G. M., Dhiman, P., Riley, R. D., Beam, A. L., Van Calster, B., Ghassemi, M., Liu, X., Reitsma, J. B., van Smeden, M., Boulesteix, A. L., & Altman, D. G. (2024). TRIPOD+AI statement: Updated guidance for reporting clinical prediction models that use regression or machine learning methods. BMJ, 385, e078378. https://doi.org/10.1136/bmj-2023-078378
Collins, G. S., Reitsma, J. B., Altman, D. G., & Moons, K. G. M. (2015). Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): The TRIPOD statement. Annals of Internal Medicine, 162(1), 55–63. https://doi.org/10.7326/M14-0697
Khan, N. A., Ishag, A. M., Ahmad, M. S., El-Sayed, F. M., Bachal, Z. A., & Abbas, T. G. (2006). Pattern of medical diseases and determinants of prognosis of hospitalization during 2005 Muslim pilgrimage Hajj in a tertiary care hospital: A prospective cohort study. Saudi Medical Journal, 27(9), 1373–1380. https://doi.org/10.15537/1658-3175.3589
Page, M. J., McKenzie, J. E., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., et al. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ, 372, n71. https://doi.org/10.1136/bmj.n71
PLOS One. (2025). Exploring the prevalence of chronic diseases and health status among international Hajj pilgrims. PLOS ONE, 20, e0317555. https://doi.org/10.1371/journal.pone.0317555
Riley, R. D., Ensor, J., Snell, K. I. E., Harrell, F. E., Martin, G. P., Reitsma, J. B., Moons, K. G. M., Collins, G. S., & van Smeden, M. (2020). Calculating the sample size required for developing a clinical prediction model. BMJ, 368, m441. https://doi.org/10.1136/bmj.m441

















